Trichloroethylene: A Review

Toxicological Review of Trichloroethylene

A review: trichloroethylene metabolites: potential cardiac teratogens.

This review is a a series of the authors' studies designed to test the hypothesis that administration of trichloroethylene (TCE), dichloroethylene (DCE), their metabolites, and related compounds are responsible for fetal cardiac teratogenesis when given to pregnant rats during organogenesis. Identification of teratogenic compounds will allow more accurate assessment of environmental contaminant...

A review: advances in microbial remediation of trichloroethylene (TCE).

Research works in the recent past have revealed three major biodegradation processes leading to the degradation of trichloroethylene. Reductive dechlorination is an anaerobic process in which chlorinated ethenes are used as electron acceptors. On the other hand, cometabolism requires oxygen for enzymatic degradation of chlorinated ethenes, which however yields no benefit for the bacteria involv...

Trichloroethylene (TCE)

Current evaluation Conclusion from the previous Monograph: Trichloroethylene (TCE) is probably carcinogenic to humans (Group 2A) based on limited evidence in humans for the carcinogenicity of TCE and sufficient evidence in experimental animals for the carcinogenicity of TCE. In making the overall evaluation, the Working Group considered the following evidence: (i) although the hypothesis linkin...

[Trichloroethylene poisoning].

Trichloroethylene and trichloroethanol were given intraperitoneally to guinea-pigs. Their effects were tested by measuring the threshold current intensity of electrical skin stimulation, the electrical excitability of the motor cerebral cortex, by recording and analysis of the electroencephalogram, and by electrocardiographic examination. The two compounds had similar effects on the nervous sys...